Answered by Ashley, Hiring Expert at Cardinal Health, on Wednesday, April 26, 2017
In most large corporations, it is common for your first round interview to be scheduled with a recruiter. I have never heard of a manager from a department outside of the position you are applying to, or outside of the recruiting team, conducting a first round interview but that doesn't mean companies don't operate this way. However, it is very common for a recruiter to conduct the initial interview so they can determine your key qualifications and if you may be a potential fit for the position. This is to help screen candidates that are clearly not a fit for a role prior to inviting the candidate for an in person interview with the hiring manager. I would try to understand the role of the person you are interviewing with prior to going into the interview so you can be mindful of the audience and the type of questions you are asking. If you are interviewing with a recruiter, or someone not on the direct team of the position you're applying to, I would keep your questions more focused on the company overall. Some great questions could be about the culture, what he/she enjoys most about the company, their position, etc.
Best of luck!